Significats de galenic formulation en anglès

Key findings: The formation of paclitaxel crystals in a pharmaceutical formulation reduces its efficacy.

However, ethanol inclusion in the pharmaceutical formulation (to enable drug loading) reduced the in vivo residence.

The pharmaceutical formulation of a new anti-tumour agent has often been perceived as the bottleneck in anti-cancer drug development.

In this work, we developed calibration models for a pharmaceutical formulation during its three manufacturing stages: blending, compaction and coating.

Preliminary tested pharmaceutical formulation applied to EAPB0503 significantly improved its water solubility and will be soon considered for future preclinical in vivo studies.